Skip to main content

Emil fischer Biography

Emil Fischer

(Euskirchen, 1852-Berlin, 1919) German chemist, Nobel Prize in Chemistry in 1902 for his work on the synthesis of sugars and purines.He studied chemistry at the universities of Bonn and Strasbourg, and was an assistant professor at the latter from 1874 to 1878.In 1875 he worked as an assistant to Adolf von Baeyer in Munich and carried out his doctoral thesis with him.In 1882 he was professor of chemistry at Erlangen, three years later at Würzburg, and in Berlin in 1892, where he succeeded Hofmann in his chair.

Emil Fischer

His main studies correspond to the molecular structure of various biochemical molecules, especially sugars.In 1876 he discovered phenylhydrazine, a compound that would be very useful later and that caused chronic eczema.His work involved an ordering of carbohydrate chemistry, partly thanks to the use of phenylhydrazine.This research provided the synthesis of a series of sugars; his greatest success was the synthesis of glucose, fructose and mannose in 1890.

His studies on glycosides and tannins are of high quality.In 1899 he began to work with peptides and proteins (especially albumin).It was Emil Fischer who clearly saw their common nature as linear polypeptides derived from amino acids, who established the principles for their synthesis, and who obtained an octadecapeptide, consisting of 15 glycines and 3 leucine residues.He had previously been the first to synthesize, together with Forneau, the glycine-glycine dipeptide, and published a work on the hydrolysis of casein.Using the methods of separation and identification of amino acids he discovered a new type of them, the cyclic amino acids: proline and oxyproline.All these works led to a better understanding of proteins and formed the basis for further studies.

In addition, he discovered the composition of multiple substances related to uric acid, caffeine and theobromine; one of them was purines, in 1884, two of which (guanine and adenine) are part of the nucleic acid structure.In Erlangen, Emil Fischer studied and synthesized the active principles of tea, coffee and cocoa (especially caffeine and theobromine).He succeeded in synthesizing purines in 1898.

In 1903, Joseph von Mering and Fischer synthesized diethylbarbiturate (also known as barbital or veronal ) , the first slow-acting compound derived from barbituric acid; The name of veronal is due to the fact that the news of the good results of the tests carried out on the product came when Fischer was in Verona.With this Fischer created an entirely new class of drugs, the barbiturates.Since then, a multitude of variants of fast and long-lasting action have been achieved, which have allowed the development of numerous pharmacological applications, such as anesthetics, anxiolytics, sedatives, anticombulsants and as enhancers of the action of other drugs (analgesics, anti-flu, tranquilizers).

Labels:

Comments

Post a Comment

Popular posts from this blog

Hans tausen Biography

Hans Tausen (Birkende, 1494-Ribe, 1561) Danish reformer.He was a student of Luther at Wittenberg.In 1530 he contributed to the writing of the Confessio Hafniensis (forty-three articles of the Danish Reformation) and was Bishop of Ribe (1542).He is the author of numerous writings on theological themes.
Post a Comment
Read more

Hevelius [Johannes Havelke] Biography

Hevelius [Johannes Havelke] (Danzig, 1611- id. , 1687) German astronomer.He drew up a first lunar map, published under the name Selenography (1647), in which he assigned names to the various features of the lunar surface and called the dark areas the sea.He determined the period of rotation of the Sun, observed its spots and discovered the faculae.In 1657 he began a catalog in which he determined the positions of 1,500 stars and that he could not finish because of a fire that destroyed his observatory (1679).
Post a Comment
Read more

Jose Pascual Vila Biography

José Pascual Vila (Mataró, 1895-Barcelona, ​​1979) Spanish chemist.He received a doctorate in Science and Pharmacy from the University of Barcelona, ​​and later completed his training in Germany and Austria.In 1922 he held the Chair of Organic Chemistry at the University of Salamanca, and shortly after at the University of Seville, between 1925 and 1934.On this date he moved to the University of Barcelona, ​​where from the same chair he taught the same subject (until 1965 ).At the latter University, he was also Vice Chancellor. Director of the Institute of Chemistry of the Center for Research and Development of the CSIC, focused his research on structural and stereochemical issues, about homoserine, cyclamic hydroxy acids, orthoesters and other topics related to Organic Chemistry, which had much repercussion in the world of Chemistry and they were the foundation of the Barcelona School. He was a member of the Royal Academy of Exact, Physical and Natural Sciences and of the Royal...
Post a Comment
Read more

Georgi Plekhanov Biography

Georgi Plejanov (Georgi or Gueorgui Valentinovich Plejanov; Gudalovka, central Russia, 1857-Terijoki, Finland, 1918) Thinker and activist of Russian socialism.He is considered the introducer in Russia of the thought of Marx and Engels.Born into a family of the gentry, he joined the revolutionary circles that fought against Tsarism since his student days. Georgi Plejanov Exiled in Switzerland since 1880, there he met Lenin and converted him to Marxist ideas; There he also founded, in 1883, the Emancipation of Labor group, the embryo of the Russian Social Democratic Labor Party (which he would contribute to found in 1894).At the same time, he developed a whole theoretical work following the ideas of the social democracy of central and western Europe (his Essay on the monist conception of history, of 1895 stands out). When in 1903 the party split between Lenin's Bolsheviks (in favor of turning the party into the vanguard of an immediate revolution, supported by the peasan...
Post a Comment
Read more

Josep Cumellas i Ribó Biography

Josep Cumellas i Ribó (Barcelona, ​​1875-1940) Spanish composer, organist and conductor.He studied music with Antonio Nicolau, Enrique Granados, Eusebi Daniel and Vicenç Costa i Nogueras at the Liceo Conservatory.In his hometown he held the position of musical director of several churches such as San Felipe Neri and Nuestra Señora de Pompeya.He developed his pedagogical career at various institutions such as the Academia Granados, the Vidiella School and the Conservatory of Terrassa, of which he was also deputy director between 1925 and 1936.He directed the Gracienc and Montserrat choirs in Barcelona, ​​for which he composed choral works of a nationalist nature.Among its more than 400 works there are samples of almost all musical genres, although stage, choral and organ music predominates.In the field of sacred music, his Salve Regina and his two Passions are notable.Cumellas harmonized numerous popular Catalan and Balearic songs that were published in various European countries.
Post a Comment
Read more

Isidore Philipp Biography

Isidore Philipp (Budapest, 1863-Paris, 1958) French pianist and composer of Hungarian origin.Installed in France from a young age, in 1890 he founded, with Berthelier and Loeb, a chamber music association.He was a remarkable pianist and an esteemed teacher.He lived in the US since 1941.He wrote educational works for his instrument.
Post a Comment
Read more

Joseph H. Maclagan Wedderburn Biography

Joseph H.Maclagan Wedderburn (Forfar, 1882-Princeton, 1948) British mathematician.Professor at Princeton University, he was editor of the Proceedings of the Edinburgh mathematical society (1905-1909) and the Annals of mathematics (1912-1928).He stated a theorem ( Wedderburn's theorem ) according to which every finite field is commutative.
Post a Comment
Read more

Isaac Jesus Barrera Quiroz Biography

Isaac Jesús Barrera Quiroz (Otavalo, 1884-Quito, 1970) Ecuadorian writer.He stood out for the publication of different biographies focused on characters from the colonial era such as the Ecuadorian writer, politician and diplomat Vicente Rocafuerte (1783-1847) and the liberator Simón Bolívar (1783-1830).He also stood out for his studies in the history of literature: Studies of Castilian Literature and History of Ecuadorian Literature .He directed the Ecuadorian Academy of History and was a corresponding member of the Academy of Language.
Post a Comment
Read more

Carolingian dynasty Biography

Carolingian Dynasty Family reigning between the middle of the 8th century and the beginning of the 10th century in practically all of Western Europe (except for the Iberian Peninsula, southern Italy and the British Isles).It gets its name from the two most prominent figures of the dynasty, Carlos Martel and Charlemagne.It was originally a Germanic noble family settled in Austrasia, in the area between the Meuse and the Rhine rivers; a first attempt to seize the Throne from the Merovingians in the mid-seventh century ended in failure, without the reprisals affecting the family patrimony.From now on, the family preferred to grow up under the Merovingian monarchy, whose decomposition left effective power in the hands of the mayordomos of the palaces of the different territories. Pepin II of Herstal (679-714) , steward of Austrasia, managed to seize the rule of the Frankish kingdom by defeating the steward of Neustria and Burgundy.His bastard son Carlos Martel (714-41) re-establis...
Post a Comment
Read more

Jean Charles Peltier Biography

Jean Charles Peltier (Ham, France, 1785-Paris, 1845) French physicist.Watchmaker by profession, Jean Peltier left his trade when he was thirty years old, to dedicate himself fully to scientific research in the field of electricity. Jean Peltier In 1834 he discovered that when an electric current circulates through a conductor made up of two different metals, joined by a weld, the latter heats up or cools down according to the direction of the current (Peltier effect).This effect, which would be confirmed by the famous Russian physicist Heinrich Lenz, led to research by James Prescott Joule and William Thomson on analogous thermoelectric phenomena and has been of great importance in the recent development of non-polluting cooling mechanisms. Peltier is also owed the introduction of the concept of electrostatic induction (1840), referred to the modification of the distribution of electric charge in a material, under the influence of a second object close to it and that has an el...
Post a Comment
Read more